| 1. Identity statement | |
| Reference Type | Journal Article |
| Holder Code | isadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S |
| Site | mtc-m16d.sid.inpe.br (namespace prefix: upn:35SP775) |
| Identifier | 8JMKD3MGP7W/3E9B8AP |
| Repository | sid.inpe.br/mtc-m19/2013/06.09.02.20.18 (restricted access) |
| Last Update | 2013:07.08.13.14.08 (UTC) marcelo.pazos@inpe.br |
| Metadata Repository | sid.inpe.br/mtc-m19/2013/06.09.02.20.19 |
| Metadata Last Update | 2024:05.08.19.18.32 (UTC) marcelo.pazos@inpe.br |
| DOI | 10.1007/s10856-013-4929-y |
| ISSN | 0957-4530 |
| Label | scopus |
| Citation Key | LoboSiNeMaCoCo:2013:ViInVi |
| Title | In vitro and in vivo studies of a novel nanohydroxyapatite/superhydrophilic vertically aligned carbon nanotube nanocomposites  |
| Project | FAPESP (2011/17877-7; 2011/20345-7) |
| Year | 2013 |
| Month | July |
| Access Date | 2026, Aug. 25 |
| Secondary Type | PRE PI |
| Number of Files | 1 |
| Size | 835 KiB |
| 2. Context | |
| Author | 1 Lobo, Anderson de Oliveira 2 Siqueira, Idalia A. W. B. 3 Neves, Marcele F. das 4 Marciano, Fernanda Roberta 5 Corat, Evaldo José 6 Corat, Marcus Alexandre F. |
| Resume Identifier | 1 2 3 4 5 8JMKD3MGP5W/3C9JH33 |
| Group | 1 2 3 4 5 LAS-CTE-INPE-MCTI-GOV-BR |
| Affiliation | 1 Laboratory of Biomedical Nanotechnology (NANOBIO), Universidade do Vale do Paraiba (UNIVAP), Av. Shishima Hifumi 2911, Sao Jose dos Campos, 12224-000, Brazil 2 Laboratory of Biomedical Nanotechnology (NANOBIO), Universidade do Vale do Paraiba (UNIVAP), Av. Shishima Hifumi 2911, Sao Jose dos Campos, 12224-000, Brazil 3 Laboratory of Biomedical Nanotechnology (NANOBIO), Universidade do Vale do Paraiba (UNIVAP), Av. Shishima Hifumi 2911, Sao Jose dos Campos, 12224-000, Brazil 4 Laboratory of Biomedical Nanotechnology (NANOBIO), Universidade do Vale do Paraiba (UNIVAP), Av. Shishima Hifumi 2911, Sao Jose dos Campos, 12224-000, Brazil 5 Instituto Nacional de Pesquisas Espaciais (INPE) 6 Centro Multidisciplinar para Investigação Biologica (CEMIB), Universidade Estadual de Campinas (UNICAMP), Rua 5 de Junho, s/n, Cidade Universitaria, Campinas, 13083-877, Brazil |
| Author e-Mail Address | 1 loboao@yahoo.com 2 3 4 5 corat@las.inpe.br |
| e-Mail Address | marcelo.pazos@inpe.br |
| Journal | Journal of Materials Science: Materials in Medicine |
| Volume | 24 |
| Number | 7 |
| Pages | 1723-1732 |
| Secondary Mark | A1 A1 A1 A2 A2 A2 A2 B1 B1 B1 B1 B1 B1 B1 B1 B1 B2 B2 |
| Host Collection | sid.inpe.br/mtc-m19@80/2009/08.21.17.02 upn:35SP775 |
| History (UTC) | 2021-07-28 22:20:51 :: administrator -> marcelo.pazos@inpe.br :: 2013 |
| 3. Content and structure | |
| Is the master or a copy? | is the master |
| Content Stage | completed |
| Transferable | 1 |
| Content Type | External Contribution |
| Version Type | publisher |
| Keywords | carbon nanotubes in vitro studies hydroxyapatite hydrophilic compounds extracellular matrix bone regeneration |
| Abstract | An association between in vitro and in vivo studies has been demonstrated for the first time, using a novel nanohydroxyapatite/superhydrophilic vertically aligned multiwalled carbon nanotube (nHAp/VAMWCNT-O2) nanocomposites. Human osteoblast cell culture and bone defects were used to evaluate the in vitro extracellular matrix (ECM) calcification process and bone regeneration, respectively. The in vitro ECM calcification process of nHAp/VAMWCNT-O2 nanocomposites were investigated using alkaline phosphatase assay. The in vivo biomineralization studies were carried out on bone defects of C57BL/6/JUnib mice. Scanning electron microscopy, micro-energy dispersive spectroscopy, X-ray photoelectron spectroscopy, and X-ray difractometry analyses confirmed the presence of the nHAp crystals. nHAp/VAMWCNT-O2 nanocomposites induced in vitro calcification of the ECM of human osteoblast cells in culture after only 24 h. Bone regeneration with lamellar bone formation after 9 weeks was found in the in vivo studies. Our findings make these new nanocomposites very attractive for application in bone tissue regeneration. |
| Area | FISMAT |
| Arrangement | urlib.net > BDMCI > Fonds > Produção anterior à 2021 > LABAS > In vitro and... |
| doc Directory Content | access |
| source Directory Content | there are no files |
| agreement Directory Content | there are no files |
| 4. Conditions of access and use | |
| Language | en |
| Target File | 10.1007_s10856-013-4929-y.pdf |
| User Group | administrator marcelo.pazos@inpe.br self-uploading-INPE-MCTI-GOV-BR |
| Reader Group | administrator marcelo.pazos@inpe.br |
| Visibility | shown |
| Archiving Policy | denypublisher denyfinaldraft12 |
| Read Permission | deny from all and allow from 150.163 |
| Update Permission | not transferred |
| 5. Allied materials | |
| Mirror Repository | iconet.com.br/banon/2006/11.26.21.31 |
| Next Higher Units | 8JMKD3MGPCW/3ESR3H2 |
| Citing Item List | sid.inpe.br/bibdigital/2013/09.24.19.30 - 50 sid.inpe.br/mtc-m21/2012/07.13.14.45.37 - 11 |
| Dissemination | WEBSCI; PORTALCAPES; COMPENDEX. |
| 6. Notes | |
| Empty Fields | alternatejournal archivist callnumber copyholder copyright creatorhistory descriptionlevel format isbn lineage mark nextedition notes orcid parameterlist parentrepositories previousedition previouslowerunit progress rightsholder schedulinginformation secondarydate secondarykey session shorttitle sponsor subject tertiarymark tertiarytype typeofwork url |
| 7. Description control | |
| e-Mail (login) | marcelo.pazos@inpe.br |
| update | |